Objectively judging the quality of a protein structure from a Ramachandran plot

By Rob W. W. Hooft, Christopher Sander, G. Vriend. 1997

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Richard A. Engh
2. R. Huber
3. Gerard J. Kleywegt
4. Shide Liang
5. A. W. Sousa da Silva
6. Valerio Mariani
7. B. Hintze
8. Paul D. Adams

Citations in the corpus

• Structure quality and target parameters (2006, methodology): “…in protein refinement that strictly enforces a physical distribution of the protein backbone ’– angles of the Ramachandran plot would transfer error-induced strain into other degrees of freedom while eliminating a Ramachandran analysis as a tool for judging protein quality (Hooft et al., 1997).”
• The PDB_REDO server for macromolecular structure model optimization (2014, unknown): “…and fine-packing percentiles are directly derived from the corresponding Z-scores from WHAT_CHECK (Vriend & Sander, 1993; Chinea et al., 1995; Hooft et al., 1997); the bump-severity percentile is based on the weighted bump severity BSw (4), which penalizes severe atomic clashes [i.e. clashes…”