Synaptic density in human frontal cortex - developmental changes and effects of aging.

By P. Huttenlocher. 1979

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Citations in the corpus

Structural Synaptic Plasticity Has High Memory Capacity and Can Explain Graded Amnesia, Catastrophic Forgetting, and the Spacing Effect (2014, background): “the total number of synaptic connections remains approximately constant over time [14,80,81].”
Temperament theory and the study of cognition-emotion interactions across development (2007, background): “Second, there are biologically based influences upon neurological individuality such as genetics, which will also be considered in a later section in this review.”
Imaging brain development: The adolescent brain (2012, background): “…cortex have shown that there is a proliferation of synapses in the subgranular layers of the prefrontal cortex during early and mid-childhood, followed by a plateau phase and a subsequent elimination and reorganisation of prefrontal synaptic connections during adolescence (Huttenlocher, 1979).”
Normal Development of Brain Circuits (2010, background): “Neurodevelopmental data in human beings and nonhuman primates, consisting mainly of postmortem and neuroimaging studies, are both limited and inherently constrained (Fogliarini et al, 2005; Huttenlocher, 1979, 1990; Huttenlocher and Dabholkar, 1997; Levitt, 2003).”
The psychobiology of maltreatment in childhood (2006, background): “In general, the maturation of the brain appears to proceed from inferior to superior and from posterior to anterior structures (Huttenlocher, 1979; Huttenlocher & de Courten, 1987; Yakovlev & Lecours, 1967), with maturation in superior parietal and frontal cortical regions being most prominent…”
Changes of synaptic density in the primary visual cortex of the macaque monkey from fetal to adult stage (1993, background): “Although until now an absolute number of synaptic loss has not been assessed in any species, the amplitude of this transient high density appears to be larger in the cortex of human (Huttenlocher, 1979; Huttenlocher et al., 1982; Huttenlocher and De Courten, 1987) and nonhuman primates (O’Kusky and ”
The adolescent brain. (2008, result): “This pattern is consistent with nonhuman primate and human postmortem studies showing that the prefrontal cortex is one of the last brain regions to mature (Bourgeois, Goldman-Rakic, & Rakic, 1994; Huttenlocher, 1979).”
Childhood Experience and the Expression of Genetic Potential: What Childhood Neglect Tells Us About Nature and Nurture (2002, background): “During the first eight months of life there is an eight-fold increase in synaptic density while the developing neurons in the brain are " seeking " their appropriate connections (Huttenlocher, 1979, 1994).”
Development of the adolescent brain: implications for executive function and social cognition. (2006, background): “As described earlier, histological studies of human prefrontal cortex have shown that there is a proliferation of synapses in the prefrontal cortex during childhood, followed by a plateau phase and a subsequent elimination and reorganisation of prefrontal synaptic connections after puberty (Huttenlo”
Diffusion tensor imaging of white matter tract evolution over the lifespan (2012, background): “Postmortem lifespan studies of the human brain demonstrate a variety of structural changes, including overall brain weight (Dekaban, 1978), myelination (Benes et al., 1994; Yakovlev and Lecours, 1967), and synaptic density (Huttenlocher, 1979; Huttenlocher and de Courten, 1987).”