Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC)

By S. Resta-Lenert, K. Barrett. Gut, 2003

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Regulation of intestinal epithelial permeability by tight junctions (2012, background): “Streptococcus thermophilus and Lactobacillus acidophilus separately increase basal TER in Caco-2 cells [226].”
TLR Signaling in the Gut in Health and Disease1 (2005, result): “These data may tie together previous observations that certain probiotic preparations increased barrier function in vitro (39, 40) and attenuate inflammation in animal models of colitis (41–43).”
Genes and Molecules of Lactobacilli Supporting Probiotic Action (2008, background): “Given the critical role of EGF signaling in many aspects of gastrointestinal physiology and epithelial repair, some beneficial effects of probiotics are also related to interference with this signaling (204, 282).”
Safety assessment of probiotics for human use (2010, background): “Direct effects include fortification of colonization resistance by secretion of antimicrobial bacteriocins, competitive growth(29) and reduction of pathogen adhesion and invasion of epithelial cells.(30,31) Furthermore certain probiotics are known to possess anti-apoptotic properties,(32,33) and to ”