Simulation of clinical trials.

By N. Holford, H. Kimko, J. Monteleone, C. Peck. 2000

285 citations recorded by the source corpus.

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Privacy in Pharmacogenetics: An End-to-End Case Study of Personalized Warfarin Dosing (2014, positive): “The practice of simulating clinical trials is wellknown in the medical research literature [4, 14, 18, 19], where it is used to estimate the impact of various decisions before initiating a costly real-world trial involving human subjects.”
Metrics for External Model Evaluation with an Application to the Population Pharmacokinetics of Gliclazide (2006, unknown): “simulation of clinical trials [4-6].”
Simulation and prediction of in vivo drug metabolism in human populations from in vitro data (2007, background): “during a teaching course for doctors and scientists who were interested in learning about practical difficulties and sources of error in clinical trial design and performanc”
Algorithms for multi-armed bandit problems (2014, background): “A thorough overview of the literature on simulating clinical trials can be found in Holford et al. (2000).”