Pax6 is required for the multipotent state of retinal progenitor cells.

By Till Marquardt, R. Ashery-Padan, Nicole Andrejewski, R. Scardigli, F. Guillemot, P. Gruss. Cell, 2001

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Electroporation and RNA interference in the rodent retina in vivo and in vitro (2003, background): “6W, 7I–L; [see Additional files 5– 8]) [31-33].”
Late-Stage Neuronal Progenitors in the Retina Are Radial Müller Glia That Function as Retinal Stem Cells (2007, background): “Expression of Pax6 in radial glia in the brain is associated with the capacity for neurogenesis (Heins et al., 2002; Götz and Barde, 2005) and with maintaining the multipotent state of retinal progenitor cells (Marquardt et al., 2001).”
Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. (2003, background): “…frog pri-genes, as demonstrated in the fly, frog, mouse, and mary neurogenesis (Sharpe and Goldstone, 2000), andchick (Cavodeassi et al., 2001; Marquardt et al., 2001; this may indicate a conserved RA-dependent mecha-Scardigli et al., 2001; de la Calle-Mustienes et al., 2002), nism for the…”
Glial cells generate neurons: the role of the transcription factor Pax6 (2002, background): “In contrast, Pax6 positively regulates Ngn2 (see also refs”
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development (2003, background): “Ablation of Pax6 from retinal progenitors under control of α-enhancer, which regulates Pax6 expression in the peripheral retina, results in the restricted potential of the retinal progenitors and differentiation into amacrine cells onl”