Magnetodendrimers allow endosomal magnetic labeling and in vivo tracking of stem cells

By J. Bulte, T. Douglas, B. Witwer, Su-Chun Zhang, Erica Strable, B. Lewis, Holly A. Zywicke, Bradley R. Miller, P. Gelderen, B. Moskowitz and 2 more. Nature Biotechnology, 2001

1,026 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d321e93392446fdd90fecf16aef48258279fa6c1

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Citations in the corpus

Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. (2005, background): “While there is no doubt that the use of stem cells in the form of cell-based therapies offers tremendous potential for disease treatment and cures for many common diseases including diabetes, cancer, heart disease, Alzheimer’s and Parkinson’s disease, central to this process would be the ability to ”
Biodegradable polymer matrix nanocomposites for tissue engineering: A review (2010, background): “For example, iron oxide super-paramagnetic nanoparticles and quantum dots have been used to track the biodistribution of cells [6].”
The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells. (2007, methodology): “To date, cellular labeling with magnetic and fluorescent nanoparticles is considered as the most promising methods [5,7–10].”
APPLICATIONS OF MAGNETIC NANOPARTICLES IN BIOMEDICINE (2003, positive): “Dendrimer coatings comprising a highly branched polymer structure that has a high rate of non-cell-specific binding and intracellular uptake have also been used to good effect [135], as has the use of lipofection agents, normally used to carry DNA into the cell nucleus, to enable intracellular incor”
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION) (2010, background): “Consequently, this iron overload can have toxic implications as excessive accumulation of the SPION, and in particular, high levels of free Fe ions in the exposed tissue can lead to an imbalance in its homeostasis and can cause aberrant cellular responses including cytotoxicity, DNA damage, oxidativ”
Applications of magnetic nanoparticles in biomedicine (2003, positive): “Dendrimer coatings comprising a highly branched polymer structure that has a high rate of non-cell-specific binding and intracellular uptake have also been used to good effect [135], as has the use of lipofection agents, normally used to carry DNA into the cell nucleus, to enable intracellular incor”
Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating. (2003, methodology): “For HeLa cells, as an example, we find an iron load of 17 pg per cell after 12 h incubation with anionic nanoparticles (1⁄2Fe 1⁄4 1:5 mmÞ to be compared with an iron load of 13 pg, obtained by [7] using dendrimers encapsulated nanoparticles (48 h incubation with 1⁄2Fe 1⁄4 0:5 mmÞ: For various other ”