Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment.
By K. Woo, Victor J. Chen, P. Ma. Journal of Biomedical Materials Research. Part A, 2003
699 citations recorded by the source corpus.
Subfields: Biomaterials, Biomedical Engineering, Surgery
View Paper: https://www.semanticscholar.org/paper/d2ff0e0fc6bf34b2b16db0e2652dce0ffcb1e782
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In Biomaterials
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Citations in the corpus
- A comprehensive review summarizing the effect of electrospinning parameters and potential applications of nanofibers in biomedical and biotechnology (2015, background): “Furthermore, nanofibrous scaffolds have shown enhanced cell adhesion, stimulated cell growth, protein adsorption, and assisted in cell differentiation (TysselingMattiace et al., 2008; Woo et al., 2003).”
- Biomimetic materials for tissue engineering. (2008, background): “2fold more human serum proteins than solid-walled scaffolds (control scaffolds with smooth pore wall morphology) [99].”
- Nanofibers and their applications in tissue engineering (2006, positive): “The results demonstrated that the nanofibers increased cell adhesion and protein adsorption (fibronectin and collagen), which are properties that are necessary for cell and ECM interaction (Woo et al 2003).”
- Three-Dimensional Cell Culture Matrices: State of the Art (2008, background): “For example, a nano-scale fibrous surface supported more serum protein adsorption than solid-wall scaffolds and promoted almost twice the amount of fibroblast adhesion.(166) Fiber diameters also affect cell proliferation and differentiation.”
- Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects (2016, background): “It was also shown that nano-fibrous (50–500 nm) PLLA scaffolds enhance protein adsorption contributing to cell attachment (Woo et al. 2003).”
- Mediation of Biomaterial–Cell Interactions by Adsorbed Proteins: A Review (2005, positive): “A study comparing fibrous and smooth-walled poly( L - lactic acid) scaffolds, however, showed differences in selectivity, as well as quantity, of proteins adsorbed from serum, 208 which suggests a mechanism beyond the increase in surface area.”