p53 represses c-Myc through induction of the tumor suppressor miR-145

By M. Sachdeva, Shoumin Zhu, Fangting Wu, Hailong Wu, Vijay Walia, Sumit Kumar, R. Elble, K. Watabe, Yin-yuan Mo. Proceedings of the National Academy of Sciences of the United States of America, 2009

885 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology

View Paper: https://www.semanticscholar.org/paper/d2d2495a6f21ca8f35b170e2826cd798a0883bee

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. C. V. Dang
2. Yin-yuan Mo
3. Carol Prives
4. Karen H. Vousden
5. Ralph J. Deberardinis
6. G. Semenza
7. M. V. Vander Heiden
8. Jason W. Locasale

In Oncology

1. Carol Prives
2. C. V. Dang
3. Karen H. Vousden
4. Vladimir N Uversky
5. W. Gu

Citations in the corpus

• Blinded by the Light: The Growing Complexity of p53. (2009, background): “Moreover, miR-145 has been implicated as a p53 target that can repress c-myc expression (Sachdeva et al., 2009).”
• LncRNA-mediated regulation of cell signaling in cancer (2017, background): “In addition, miR-145 serves as a direct target of p53 and thus, DNA damage induces p53-mediated miR-145 expression (Sachdeva et al 2009), which in turns is able to target Linc-RoR through CeRNA mechanisms (Wang et al 2013b).”
• MYC on the Path to Cancer (2012, background): “The MYC mRNA, which is short lived, is affected by miRNAs (let-7, miR-34, andmiR-145) resulting in translational modulation (Cannell et al., 2010; Christoffersen et al., 2010; Kim et al., 2009; Kress et al., 2011; Sachdeva et al., 2009).”