New antibiotics from bacterial natural products

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How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Endophytic fungal diversity: review of traditional and molecular techniques (2012, background): “A metagenomic library has been successfully constructed for natural product screening in soil microbes (Rondon et al. 2000; Clardy et al. 2006).”
Microbial drug discovery: 80 years of progress (2009, background): “125 In addition to these two relatively new techniques, the chemical and biological modification of old antibiotics could still supply new and powerful drugs.”
A deep learning approach to antibiotic discovery (2020, background): “secondary metabolites that prevented the growth of pathogenic bacteria (Clardy et al., 2006; Wright, 2017).”
NATURAL PRODUCTS: A CONTINUING SOURCE OF NOVEL DRUG LEADS (2013, result): “Many more examples of the value of this type of investigation at that time, were provided in two subsequent reviews [232, 233], which should be read in conjunction with the later work reported by the groups of Hertweck [185], Keller [126], Moore [229], Piel [133] and Brady / Schmidt [129] to name bu”
A Deep Learning Approach to Antibiotic Discovery. (2020, neutral): “Historically, antibiotics were discovered largely through screening soil-dwelling microbes for secondary metabolites that prevented the growth of pathogenic bacteria (Clardy et al., 2006; Wright, 2017).”