Microbial drug discovery: 80 years of progress
By A. Demain, S. Sánchez. Journal of antibiotics (Tokyo. 1968), 2009
972 citations recorded by the source corpus.
Microbes have made a phenomenal contribution to the health and well-being of people throughout the world. In addition to producing many primary metabolites, such as amino acids, vitamins and nucleotides, they are capable of making secondary metabolites, which constitute half of the pharmaceuticals on the market today and provide agriculture with many essential products. This review centers on these beneficial secondary metabolites, the discovery of which goes back 80 years to the time when penicillin was discovered by Alexander Fleming.
Subfields: Biotechnology, Molecular Biology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/f744eada6e4c6b8d391d769e06a80fe0f6e176f1
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Citations in the corpus
- Growing Unculturable Bacteria (2012, background): “(19), and it has been estimated that the total diversity of natural small molecules (under 1 kDa) from bacteria is in excess of 10(9)”