The role of the IGF system in cancer growth and metastasis: overview and recent insights.

By A. Samani, S. Yakar, D. Leroith, P. Brodt. Endocrine reviews, 2007

1,053 citations recorded by the source corpus.

Subfields: Cancer Research, Endocrinology, Diabetes and Metabolism, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d2238d60fb6cad7e2bc751e5696ad9bd23ce3f68

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. E. Lengyel

In Endocrinology, Diabetes and Metabolism

1. E. Gale

In Molecular Biology

1. E. Lengyel

Citations in the corpus

• Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. (2009, background): “Limited data exist pertaining to antibodies that block both IGF-I and IGF-II.”
• The influence of glucose-lowering therapies on cancer risk in type 2 diabetes (2009, background): “These observations have given rise to the hypothesis that growth of these tumours, which are characterised by abnormal expression and function of the insulin–IGF-1 series of receptors [2, 3], is promoted by the trophic action of insulin interacting with these receptors.”
• Adipose tissue and adipocytes supports tumorigenesis and metastasis (2013, background): “Through the IGF receptor, IGF activates downstream signaling pathways that promote mitogenic and proangiogenic pathways and inhibit apoptosis [48].”