Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome.

By E. Maury, S. Brichard. Molecular and Cellular Endocrinology, 2010

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Dietary factors and low-grade inflammation in relation to overweight and obesity (2011, neutral): “5)((94)), is induced in the pre-adipocyte((87)) and in the adipocyte in the presence of a medium from macrophages((95)).”
High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway (2012, background): “Until now, the majority of studies have focused on the adipose tissue as the source of inflammatory mediators in obesity [10].”
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan (2011, background): “Accumulation of lipids in adipocytes as well as the ectopic storage of fat in liver, muscles, and pancreas stimulate the innate immunity defense leading to the secretion of proinflammatory cytokines and subsequently to recruitment of monocytes, especially into the adipose tissue [7–9].”
Oxidative Stress in Obesity: A Critical Component in Human Diseases (2014, background): “Similar to leptin effects, resistin seems to mediate insulin resistance [61].”