Respiratory toxicity of multi-wall carbon nanotubes.

By Julie Muller, F. Huaux, N. Moreau, P. Misson, J. Heilier, M. Delos, M. Arras, A. Fonseca, J. Nagy, D. Lison. Toxicology and Applied Pharmacology, 2005

1,115 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Materials Chemistry, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/d045b356626d552c0d8d97b8d2117949e013ab40

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In Health, Toxicology and Mutagenesis

In Materials Chemistry

Citations in the corpus

Exploiting the enhanced permeability and retention effect for tumor targeting. (2006, neutral): “66, 1909–1926 73 Muller, J. et al. (2005) Respiratory toxicity of multi-wall carbon nanotubes.”
Nanotechnology and Water Treatment: Applications and Emerging Opportunities (2008, neutral): “Muller et al. (2005) MWCNT 12.5 mg; Intratracheal instillation Guinea pigs Pneumonitis and pulmonary lesions.”
Carbon Nanotubes in Biology and Medicine: In vitro and in vivo Detection, Imaging and Drug Delivery (2009, background): “ntratracheally (IT) instilled into animals, showing obvious pulmonary toxicity including unusual inflammation and fibrotic reactions due to the aggregation of hydrophobic raw CNTs in the lung airways [39, 40, 110, 111]. Those results suggest that aerosol exposure of raw CNTs in the workplace should ”
Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. (2008, background): “Their high aspect ratio (ratio of length and width) makes them an attractive structural material, but their nanometre-scale diameter and needle-like shape have drawn comparisons with asbesto”
Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. (2006, methodology): “The CNT were highly fibrogenic and inflammogenic, being roughly equivalent to a chrysotile asbestos control (no size distribution given), and more active than NPCB (Muller et al., 2005).”
Nanomaterials and nanoparticles: Sources and toxicity (2007, background): “For example, carbon nanotubes are not eliminated from the lungs or very slowly eliminated (81% found in rat lungs after 60 days) [159].”
Nanodiamond Particles: Properties and Perspectives for Bioapplications (2009, neutral): “However, even within the same animal model, there has been a great divergence in toxicity results for pulmonary studies of carbon nanotubes in animals 243 , 244 , 245 , 262 , 321 , 322 , 323 or C60 in aquatic species and animals.”
Biomedical applications of functionalised carbon nanotubes. (2005, background): “In most cases, inflammatory responses, accompanied by interstitial fibrosis and granulomas formation, were observed (Lam et al., 2004; Warheit et al., 2004; Muller et al., 2005).”