Gaze fixation and the neural circuitry of face processing in autism

By Kim M. Dalton, Brendon M. Nacewicz, Tom Johnstone, Hillary S. Schaefer, Morton Ann Gernsbacher, H. Goldsmith, Andrew L. Alexander, Richard J. Davidson. Nature Neuroscience, 2005

1,583 citations recorded by the source corpus.

Subfields: Clinical Psychology, Cognitive Neuroscience, Epidemiology

View Paper: https://www.semanticscholar.org/paper/cf91085c85202178f1e3b5d821c5b0e6562d7862

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Citations in the corpus

Eye tracking studies of normative and atypical development (2007, methodology): “First 6 groups spanned 2 years each (N = 20–30/bin) seventh group spanned 6 years (N = 62) Inverse regression best fit for sac RTs, antisaccade errors, distance errors of MGS Tasks always in this order Multiple regression, model fitting Antisac errors and spatial error of initial MGS mature at 14, s”
Developing constructs for psychopathology research: research domain criteria. (2010, positive): “More specific constructs—such as separation fear, facial expression recognition, behavioral inhibition, emotion regulation, and others—have shown direct links to specific neural systems (see e.g., Adolphs, Sears, & Piven, 2001; Dalton et al., 2005; Davidson, Irwin, Anderle, & Kalin, 2003).”
When the world becomes 'too real': a Bayesian explanation of autistic perception. (2012, background): “tones [19], coherently moving dots [20] and complex objects [21], as well as social stimuli, including faces [21, 22], eye-gaze direction [23, 24], biological motion [25, 26], and speech [27].”
Oxytocin improves "mind-reading" in humans. (2007, positive): “A recent study showed a strong and positive association between activation of the FFA and the amygdala and the amount of time spent fixating on the eye region of emotional faces in autistic patients (Dalton et al 2005), pointing to the particular role of the eye region in affective mind-reading.”
Emotional competence in children with autism: Diagnostic criteria and empirical evidence (2008, background): “Typically developing (pre) adolescents attend more to faces in general (Schultz, 2005), to eye, nose and mouth regions (Dalton et al., 2005; Klin, Jones, Schultz, Volkmar, & Cohen, 2002b; Lindner & Rosen, 2006; Pelphrey et al., 2002), and to eyes relatively to mouths.”
The Empathy Imbalance Hypothesis of Autism: A Theoretical Approach to Cognitive and Emotional Empathy in Autistic Development (2009, background): “There are cortical and subcortical pathways that connect the sensory thalamus to the amygdala (LeDoux & Phelps, 2000), and there is evidence that the amygdala may be hyperresponsive in autism (Dalton et al., 2005).”
A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function (2010, background): “Similarly, both hyper- (72, 73) and hypoactivations (48, 74) of the amygdala during face processing have been demonstrated in social disorders such as autism.”
A review of methods in the study of attention in autism (2010, background): “…ASD tend to agree that attention to the eye-region in particular is atypical in ASD (Pelphrey et al., 2002; Trepagnier, Sebrechts & Peterson, 2002; Dalton et al., 2005; Dalton, Nacewicz, Alexander & Davidson, 2006; Nacewicz et al., 2006; Boraston, Corden, Miles, Skuse & Blakemore, 2008; Corden,…”
Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis. (2013, background): “, 2012), whereas amygdala dysfunction has been implicated in autism spectrum disorder (Dalton et al., 2005; Nacewicz et al., 2006; Kleinhans et al., 2009).”
How much compliance is too much compliance: Is long-term ABA therapy abuse? (2019, background): “This overstimulation is seen in the over-activation of the amygdala when eye-gaze is held for longer (Dalton et al., 2005; Markram & Markram, 2010).”
Face scanning in chimpanzees and humans: continuity and discontinuity (2010, background): “Indeed, it is known that autistic children, who experience difficulties in forming normal social and emotional relationships with people, pay less attention to the eye regions than children with typical developmental courses (Klin et al. 2002; Pelphrey et al. 2002; Dawson et al. 2004; Dalton et al. ”