Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome

By Robert D. Goldman, D. Shumaker, M. Erdos, M. Eriksson, A. Goldman, L. Gordon, Y. Gruenbaum, S. Khuon, Melissa G. Mendez, R. Varga and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2004

1,112 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cf625a0f4615e0ab4ad0240ec7830dc16382fa56

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In Molecular Biology

1. D. Tuveson
2. I. I. C. Chio
3. C. Tonelli

Citations in the corpus

• Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. (2008, positive): “It has also been shown that LA 50/progerin is abnormally associated with the nuclear lamina (Goldman et al. 2004; Scaffidi and Misteli 2005; Dahl et al. 2006).”
• Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes (2005, neutral): “This protection may be particularly important in cell types, such as muscle cells, that are the frequent subject of mechanical stress, affecting the shape of both the cell and its nucleus [54,55].”
• Transcriptional Regulation by Nrf2 (2017, background): “nuclear architectural protein lamin A (39).”