The structure of DNA in the nucleosome core

By T. Richmond, C. Davey. Nature, 2003

1,290 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/cf4c0b7d4562a640dc89894e391d0a6a137f129e

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In Molecular Biology

Citations in the corpus

Single-cell chromatin state analysis with Signac (2021, background): “The length of DNA wrapped around a single nucleosome has been experimentally determined as 147 bp 57 .”
The Major Architects of Chromatin: Architectural Proteins in Bacteria, Archaea and Eukaryotes (2008, background): “In contrast to bacterial DNA, nucleosomal DNA is intrinsically overtwisted (∼10.35 bp/turn) (Richmond and Davey, 2003; Bates and Maxwell, 2005), possibly due to the slight overstretching of DNA in the nucleosome core particle (Prunell, 1998; Gore et al., 2006).”
Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle (2005, background): “Recently, the structural geometry of the nucleosomal DNA has been evaluated in the Xla-NCP structure at 1.9 s resolution ( 16 ).”
Rapid spontaneous accessibility of nucleosomal DNA (2005, neutral): “dtd" [ ]> Eukaryotic genomic DNA is organized in a repeating array of nucleosomes, in which short stretches of DNA, 147 base pairs (bp) in length, are wrapped locally in ∼1 3/4 superhelical turns around octameric spools of histone prote”
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer (2006, background): “The tail region of the histones (which extend away from the nucleosome core) undergo a complex and coordinated series of regulatory modification”
Chromatin remodelling: the industrial revolution of DNA around histones (2006, background): “Currently, wave sizes during remodelling are not known and remain to be tested, although waves of 1 bp have been detected on the nucleosome surface by structural studie”
Conformational analysis of nucleic acids revisited: Curves+ (2009, background): “This is particularly the case in protein–nucleic acid complexes, and not only in binary complexes, but also in large assemblies such as the nucleosome ( 18 ), and RecA/DNA filaments (19).”
Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome (2007, background): “With this high resolution map we sought to address the following questions: (1) what are the DNA signatures of nucleosome positioning in vivo? (2) How many translational and rotational settings do nucleosomes occupy? (3) Do chromosomal elements possess specific chromatin architecture? (4) What is th”
The nucleosome: from genomic organization to genomic regulation. (2004, background): “…prepared in E. coli (Luger has a unique role within the nucleosome, as there is a 2-fold symmetry in the nucleosome organized directlyet al., 1997); a related structure has also been determined at 1.9 Å resolution (Richmond and Davey, 2003; along the dimer interface of the two H3 histones.”