Expression of the IRT1 Metal Transporter Is Controlled by Metals at the Levels of Transcript and Protein Accumulation Article, publication date, and citation information can be found at…

By E. L. Connolly, J. P. Fett, M. Guerinot. The Plant Cell Online, 2002

740 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/cebf49dd97604f185aa2aed2e7b4195f655694ab

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Citations in the corpus

Iron homeostasis related genes in rice (2003, background): “This pattern suggests control at the protein stability level (Connolly et al., 2002).”
Iron supply prevents Cd uptake in Arabidopsis by inhibiting IRT1 expression and favoring competition between Fe and Cd uptake (2017, background): “Interestingly, IRT1 is also primarily responsible for Cd uptake (Connolly et al. 2002; Vert et al. 2002; Nakanishi et al. 2006; Clemens et al. 2013).”
Mobilization of vacuolar iron by AtNRAMP3 and AtNRAMP4 is essential for seed germination on low iron (2005, background): “Strong post-transcriptional regulation of metal transport proteins has already been reported for IRT1 in Arabidopsis (Connolly et al, 2002) and for SMF1 in yeast (Liu and Culotta, 1999).”
Natural variation in cadmium tolerance and its relationship to metal hyperaccumulation for seven populations of Thlaspi caerulescens from western Europe (2003, background): “…Fe in leaves is typically in the range 0.05–0.15 g kg -1 dry biomass (Marschner 1995), and a chlorotic phenotype is detectable in A. thaliana at a shoot Fe content of 0.08 g kg -1 (Connolly et al. 2002), suggesting that the Ganges plants are bordering on incipient Fe-deficiency when exposed to Cd.”
Iron dynamics in the rhizosphere as a case study for analyzing interactions between soils, plants and microbes (2009, background): “Additionally, posttranscriptional regulation controls Fe acquisition proteins FRO2, IRT1 FER/FIT (Connolly et al. 2002; Connolly et al. 2003; Jakoby et al. 2004; Brumbarova and Bauer 2005).”
Toxic Heavy Metal and Metalloid Accumulation in Crop Plants and Foods. (2016, background): “thaliana (27) and via ZRT- and IRT-like protein 8 (ZIP8) and divalent metal transporter 1 (DMT1) into mammalian cells (28, 38).”
Zn Uptake and Translocation in Rice Plants (2011, background): “…of the Zn-regulated transporters in the iron (Fe)-regulated transporter-like protein (ZIP) gene family (Guerinot 2000) have been characterized and shown to be involved in metal uptake and transport in plants (Eide et al. 1996; Korshunova et al. 1999; Vert et al. 2001, 2002; Connolly et al. 2002).”
Physiology and molecular biology of stress tolerance in plants (2006, background): “These findings suggest that the expression of IRT1 is controlled by two distinct mechanisms that provide effective means of regulating metal transport in response to changing environmental conditions (Connolly et al., 2002).”
Fortification of micronutrients for efficient agronomic production: a review (2016, background): “…occur through a shared uptake system involving similar divalent metal transporting enzymes (e.g., ironregulated transporter, IRT) that are present in both root and shoot cells (Connolly et al. 2002, 2003; Ishimaru et al. 2005; Kim and Guerinot 2007; Shanmugam et al. 2011; Sinclair and Krämer 2012).”
Iron uptake, trafficking and homeostasis in plants (2003, background): “of iron homeostasis already starts at the uptake process, as documented by several control levels of IRT1 expression (Connolly et al. 2002).”
The Essential Basic Helix-Loop-Helix Protein FIT1 Is Required for the Iron Deficiency Response (2004, methodology): “Immunoblot analysis was performed as previously described (Connolly et al., 2002).”
Functions and Homeostasis of Zinc, Copper, and Nickel in plants (2005, background): “Plants transformed with p35S::IRT1 or p35S::FRO2 display constitutive ectopic overexpression of IRT1 or FRO2 transcripts, respectively, but protein levels remain iron-regulated as in wild type plants (Connolly et al. 2002; 2003).”
Transition metal transporters in plants. (2003, neutral): “IRT1 is now thought to be the major transporter for high afﬁnity Fe uptake by roots (Connolly et al ., 2002; Vert et al ., 2002).”
Manganese accumulation in leaves of Hakea prostrata (proteaceae) and the significance of cluster roots for micronutrient uptake as dependent on phosphorus supply (2005, background): “prostrata may occur partly occur via the Fe-uptake system (Connolly et al. 2002) or through Zn transporters (ZRT, zinc-regulated transporters).”
Intraspecific variation of metal preference patterns for hyperaccumulation in Thlaspi caerulescens: evidence from binary metal exposures (2008, background): “In case of essential metals, such as iron and zinc, the transporters responsible for uptake and transport are strongly up-regulated under conditions of deficiency (Grotz et al. 1998; Assunção et al. 2001; Connolly et al. 2002; Vert et al. 2002).”
Alleviation by calcium of cadmium-induced root growth inhibition in Arabidopsis seedlings (2005, background): “However, this protein can also transport Mn, Zn and Cd (Connolly et al. 2002; Korshunova et al. 1999).”