Molecular nanomechanics of nascent bone: fibrillar toughening by mineralization

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Toughness amplification in natural composites (2011, background): “This model captures the micromechanics of staggered composites using continuum approaches and as such it cannot capture important mechanisms occurring at molecular scales (which are also critical to the overall performance of the material, Buehler and Yung, 2009; Buehler, 2007; Smith et al., 1999).”
Biomimetic nanofibrous scaffolds for bone tissue engineering (2011, unknown): “mineralized collagen fibrils is what gives bone its lightweight strength [8].”
Merger of structure and material in nacre and bone - Perspectives on de novo biomimetic materials (2009, background): “the significant effect the presence of mineral crystals in collagen fibril has on the mechanical response [42].”
On the Mechanistic Origins of Toughness in Bone (2010, background): “with fibrils without a mineral phase (66, 67).”
Multiscale modeling of elastic properties of cortical bone (2010, methodology): “Buehler [ 66 ] used MD simulation to study pure and mineralized collagen fibrils, whereas Bhowmik et al. [67] performed MD to address the load carrying behavior of collagen in the proximity of HA. Also, Dubey and Tomar [68] analyzed the type-I collagen and HA arrangement using molecular dynamics.”
Hydrogel scaffolds for tissue engineering: Progress and challenges (2013, unknown): “Images were adapted with modification from Buehler.(99)”