Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia.

By A. Vgontzas, D. Papanicolaou, E. Bixler, Kenneth Hopper, A. Lotsikas, Huong-Mo Lin, A. Kales, George P. Chrousos. Journal of Clinical Endocrinology and Metabolism, 2000

1,231 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Physiology

View Paper: https://www.semanticscholar.org/paper/c81087cf417ee0f18770532fe4a288cffab6ace0

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In Cognitive Neuroscience

B. K. Pedersen

In Endocrine and Autonomic Systems

In Physiology

Citations in the corpus

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression (2009, neutral): “Of relevance in this regard is that BMI has been shown to correlate with increased peripheral markers of inflammation, in part related to the capacity of adipose tissue to produce IL-6 and other cytokines (114,115).”
Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. (2007, background): “hypoxia, such as obstructive sleep apnea (20, 40, 50, 56).”
Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. (2000, neutral): “Because it was already observed by others (23, 24), we found a positive relationship between circulating IL-6 and the degree of obesity estimated by the BMI.”
The anti-inflammatory effect of exercise. (2005, background): “Increased levels of both TNF- and IL-6 have been observed in obese individuals, in smokers, and in patients with Type 2 diabetes mellitus (150), and plasma concentrations of IL-6 have been shown to predict all-cause mortality as well as cardiovascular mortality (49, 151).”
Obstructive Sleep Apnea and the Recurrence of Atrial Fibrillation (2003, neutral): “966 Median, IQR 43 (12, 63) 25 (8, 59) Arousal index, events/h Mean SD 56 43 41 29 0.”