Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication

By J. Ratajczak, M. Wysoczynski, F. Hayek, A. Janowska-Wieczorek, M. Ratajczak. Leukemia, 2006

1,324 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c7ec27728b98bdf0d9dfd14283cf0c81b8bedac4

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In Molecular Biology

Citations in the corpus

Extracellular vesicles: Exosomes, microvesicles, and friends (2013, background): “A major breakthrough was the demonstration that the cargo of EVs included both mRNA and miRNA and that EVassociated mRNAs could be translated into proteins by target cells (Ratajczak et al., 2006; Valadi et al., 2007).”
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing (2016, background): “, mouse embryonic stem cells EVs enhanced survival and expansion of hematopoietic progenitor cells [179], endothelial progenitor cells-derived EVs protect against angiotensin II-induced cardiac hypertrophy [180], and mesenchymal stem cell EVs reduce infarct size in a mouse model of myocardial ischem”
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells (2011, background): “More recent data have demonstrated that macrophages are able to produce microvesicles, also known as exosomes, which shuttle proteins or microRNAs (miRNAs) into adjacent cells within the microenvironment [13,14].”
Detection of microRNA Expression in Human Peripheral Blood Microvesicles (2008, background): “Some suggest that the vesicle ‘‘hijacks’’ the cytoplasm prior to release from the cell through membrane blebbing [23].”
The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? (2015, positive): “TAMs (and MSCs) can produce exosomes, enabling ingress of mRNAs and microRNAs (miRNAs) into various cell types (Ratajczak et al., 2006; Jing et al., 2012) for cancer cell growth and metastasis (Fabbri,”
Exosomes: extracellular organelles important in intercellular communication. (2010, background): “The biochemical and functional aspects of ABs and SMVs, which are documented in previous reviews [14,21,22], will not be discussed in detail in this review.”
Microvesicles: mediators of extracellular communication during cancer progression (2010, background): “Microvesicles packaged with microRNAs (miRNAs) or mRNAs have been shown to be released mainly from progenitors of differentiated cells and tumor cells (Mytar et al., 2008; Ratajczak et al., 2006a).”
Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs (2010, background): “Recently, MVs/exosomes have been described as a potent paracrine mechanism that may re-direct cell fate through the active transfer of proteins, functional mRNAs and miRNAs [7,35].”
Biological properties of extracellular vesicles and their physiological functions (2015, background): “Mechanisms that control RNA-sorting to EVs Since the discovery of RNA in EVs (16,17,178), increasing evidence suggests that RNAs are not passively loaded into EVs, but that certain populations of RNAs become enriched in EVs compared to parental cells.”