Can Animal Models of Disease Reliably Inform Human Studies?
By H. V. D. Worp, D. Howells, E. S. Sena, M. Porritt, Sarah S J Rewell, V. O'Collins, M. Macleod. PLoS Medicine, 2010
1,278 citations recorded by the source corpus.
H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.
Subfields: Computational Theory and Mathematics, Developmental Neuroscience, Small Animals
View Paper: https://www.semanticscholar.org/paper/c76381cef7a017eecfa94108d9bb73a5ae77b458
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In Small Animals
Citations in the corpus
- Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019 (2019, background): “This can include a description of how the induction of the disease, disorder, or injury is sufficiently analogous to the human condition, how the model responds to known clinically-effective treatments, how similar symptoms are to the clinical disease and how animal characteristics were selected to ”
- Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2020, background): “Definitions are adapted from [14,15] and placed in the context of animal research.”
- Biology-inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing (2016, neutral): “Leist and Hartung, 2013; Matthews, 2008; Olson et al., 2000; Perel et al., 2007; Hartung and Leist, 2008; Schnerch et al., 2010; Sena et al., 2010; Seok et al., 2013; van der Worp et al., 2010; Hartung, 2013).”
- The ARRIVE guidelines 2.0: updated guidelines for reporting animal research (2020, background): “…information requirements on the ethical review of the research (Osborne et al. 2009; Rands, 2011), data presentation and access (Giofre et al. 2017; Vasilevsky et al. 2017; Michel et al. 2020), statistical methods (Giofre et al. 2017; Michel et al. 2020), and conflicts of interest (Ancker &…”