The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
By N. Percie du Sert, Viki Hurst, A. Ahluwalia, S. Alam, Marc T. Avey, Monya Baker, William J. Browne, Alejandra Clark, Innes C. Cuthill, U. Dirnagl and 18 more. Journal of Physiology, 2020
1,289 citations recorded by the source corpus.
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour, and reproduce the methods and results. Despite considerable levels of endorsement by funders and journals over the years, adherence to the guidelines has been inconsistent, and the anticipated improvements in the quality of reporting in animal research publications have not been achieved. Here, we introduce ARRIVE 2.0. The guidelines have been updated and information reorganised to facilitate their use in practice. We used a Delphi exercise to prioritise and divide the items of the guidelines into 2 sets, the ‘ARRIVE Essential 10,’ which constitutes the minimum requirement, and the ‘Recommended Set,’ which describes the research context. This division facilitates improved reporting of animal research by supporting a stepwise approach to implementation. This helps journal editors and reviewers verify that the most important items are being reported in manuscripts. We have also developed the accompanying Explanation and Elaboration document, which serves (1) to explain the rationale behind each item in the guidelines, (2) to clarify key concepts, and (3) to provide illustrative examples. We aim, through these changes, to help ensure that researchers, reviewers, and journal editors are better equipped to improve the rigour and transparency of the scientific process and thus reproducibility.
Subfields: Biomedical Engineering, Small Animals, Statistics and Probability
View Paper: https://www.semanticscholar.org/paper/cde4bb4634a3b3e04fddf009e59a2e71f8cb7a04
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biomedical Engineering
In Small Animals
In Statistics and Probability
- Michael Emerson
- M. Macleod
- D. Howells
- William J. Browne
- Stanley E. Lazic
- E. Sena
- Innes C. Cuthill
- H. Schielzeth
Citations in the corpus
- The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* (2020, methodology): “To ensure that the recommendations are as clear and useful as possible to the target audience, this document was road tested alongside the revised guidelines with researchers preparing manuscripts describing in vivo research [13].”
- Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2020, methodology): “To ensure that the recommendations are as clear and useful as possible to the target audience, this document was road tested alongside the revised guidelines with researchers preparing manuscripts describing in vivo research [13].”