Retinal degeneration mutants in the mouse.

By B. Chang, N. Hawes, R. Hurd, M. Davisson, S. Nusinowitz, J. Heckenlively. Vision Research, 2002

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Pupil fluctuations track fast switching of cortical states during quiet wakefulness (2014, neutral): “In these mice, the retinal ganglion cell layer undergoes severe degeneration by P21 (Chang et al., 2002).”
Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. (2006, neutral): “Histological studies, both in animal models of photoreceptor degeneration (Chang et al., 2002; Olshevskaya et al., 2004) and in postmortem patient eyes with almost complete photoreceptor loss because of RP (Santos et al.”
The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. (2012, background): “The rd8 mutation is a single nucleotide deletion in the Crb1 gene, which results in a form of retinal degeneration having a distinct clinical appearance, including multiple lightcolored spots in the fundus of the eye that correspond histologically to retinal folds, pseudorosettes, as well as focal r”
Neural remodeling in retinal degeneration. (2003, background): “Similarly the rd10 mouse, with a missense mutation the Pde6b gene (Chang et al., 2002) and a much slower retinal degeneration than rd1, shows the same pattern of neurite retraction, even though rod death does not overlap with rod bipolar cell neurite development.”