CD40/CD154 interactions at the interface of tolerance and immunity.
By Sergio A. Quezada, L. Jarvinen, E. Lind, R. Noelle. Annual Review of Immunology, 2004
757 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/c647f3331a0c54d9999d47498f4f8244e9726a79
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In Immunology
Citations in the corpus
- Molecular mechanism and function of CD40/CD40L engagement in the immune system (2009, background): “ulatory molecules on their surface, and facilitates the cross-presentation of antigen (2).”
- The inflammasome: an integrated view (2011, neutral): “Firstly, two well-characterized anti-apoptotic members of the Bcl-2 family, namely Bcl-2 and Bcl-XL, have been shown to suppress inflammasome activity in response NLRP1 and NLRP3 activators (104, 131).”
- Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease (2006, background): “How the CD40–CD40L interaction contributes to the high avidity interaction between developing Tregs and stromal cells in the thymus needs to be determined (95, 96).”
- Follicular B helper T cells in antibody responses and autoimmunity (2005, background): “The crucial role of CD40L for provision of B-cell help is well establishe”
- The regulation of IgA class switching (2008, background): “In general, germinal-centre reactions are highly dependent on cognate interactions between antigen-specific B cells and CD4 + T cells that express CD40 ligand ( CD40L ; also known as CD154), a tumour-necrosis factor (TNF) family member that engages CD40 on B cell”
- Antibodies and cancer therapy: versatile platforms for cancer immunotherapy (2010, background): “Engagement of CD40 on antigen-presenting cells leads to the upregulation of co-stimulatory molecules, production of pro-inflammatory cytokines and facilitation of cross-presentation of antigen”