Non-orthologous gene displacement.
By Eugene V. Koonin, Arcady R. Mushegian, Peer Bork. 1996
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- D. Soltis
- Pamela S. Soltis
- Michael J. Donoghue
- J. Doyle
- Brian C. O'Meara
- Cécile Ané
- Alexandros Stamatakis
- J. Leebens-Mack
Citations in the corpus
- Comparative genomics, minimal gene-sets and the last universal common ancestor (2003, background): “For a substantial number of essential functions, different organisms use genes that are not orthologues and, in some cases, are not even homologue”
- The iPlant Collaborative: Cyberinfrastructure for Plant Biology (2011, background): “Only a small percentage of plant genes have laboratory or field-based evidence for their functions, and multigene families, non-orthologous gene displacement (Koonin et al., 1996), lateral gene transfer, and several other natural biological processes make functional assignments more difficult.”
- Orthologs, Paralogs, and Evolutionary Genomics 1 (2005, background): “, recruitment of non-orthologous genes for the equivalent, essential functions in different organisms (47, 52).”
- The phagotrophic origin of eukaryotes and phylogenetic classification of Protozoa. (2002, background): “Such trivial gene replacement (Koonin et al., 1996) is sometimes said to be unexpected (Doolittle, 1998a), but was predicted on general evolutionary grounds (Cavalier-Smith, 1990a) before evidence for it became widespread.”
- Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world (2008, background): “recruitment of unrelated genes (or distantly related, nonorthologous genes) for the same function (63).”
- Protein Complexes in Bacteria (2015, background): “This suggests that many functions can be replaced by non-homologous displacement [20] and that genomes are more malleable in evolutionary terms than previously expected.”