Biotic ligand model of the acute toxicity of metals. 1. Technical Basis

By Dominic M. Di Toro, H. Allen, H. Bergman, J. Meyer, P. Paquin, R. Santore. Environmental Toxicology and Chemistry, 2001

1,351 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Oceanography, Pollution

View Paper: https://www.semanticscholar.org/paper/c5f1a2c5a1587ea2795658b56b4b5cdc0100be9c

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In Health, Toxicology and Mutagenesis

1. C. Wood
2. P. Chapman
3. Feiyue Wang
4. Randall Wenstel
5. W. Wood
6. Colin R. Janssen
7. Uwe A. Schneider
8. A. Fairbrother

In Oceanography

1. Uwe A. Schneider

In Pollution

1. C. Wood
2. P. Chapman
3. Feiyue Wang
4. Randall Wenstel
5. W. Wood
6. Colin R. Janssen
7. A. Fairbrother
8. Keith G. Sappington

Citations in the corpus

• Discriminating between intra‐ and extracellular metals using chemical extractions (2004, background): “…of the metal bound to sensitive sites such as transporters from the more generalized binding of metal to cell wall components such as polysaccharides and phospholipids would provide a direct verification of one of the key hypotheses underlying the biotic ligand model (Di Toro et al. 2001).”
• Conducting Ecological Risk Assessments of Inorganic Metals and Metalloids: Current Status (2003, background): “The development of the Free Ion Activity Model (FIAM; Morel and Hering 1993; Campbell 1995) and extensive studies on the effects of metals on fish gills have resulted in the Biotic Ligand Model (BLM — Di Toro et al. 2001; Santore et al. 2001).”
• Framework for metals risk assessment. (2007, methodology): “More recently, the Office of Water has been developing a mechanistic-based approach for addressing metals bioavailability using the Biotic Ligand Model (BLM) (Di Toro et al., 2001; Santore et al., 2001; U.S. EPA, 2000b).”
• Issues in Ecological Risk Assessment of Inorganic Metals and Metalloids (2000, methodology): “The Biotic Ligand Model (BLM; DiToro et al., 1999; <www.epa.gov/science1/epecblm.pdf>), which was adapted from the Free Ion Activity Model (FIAM; Morel, 1983; Campbell, 1995; Hare and Tessier, 1996; Hudson, 1998; van Leeuwen, 1999) and the gill surface interaction model (Pagenkopf, 1983), may…”
• The biotic ligand model: a historical overview. (2002, methodology): “These differences highlight the necessity to incorporate differences in species sensitivities to acute metal toxicity in the BLM. Di Toro et al.(2001)and Santore et al. (2001) found that reducing the critical concentration of metal binding to the biotic ligand was suitable for predicting acute…”