Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

By E. Mariani, M. Polidori, A. Cherubini, P. Mecocci. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005

706 citations recorded by the source corpus.

Subfields: Neurology, Pharmacology, Physiology

View Paper: https://www.semanticscholar.org/paper/c39b89ac52aa40de445ed783ca59f4217f6e29c6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. K. Rahman
2. L. Zuo
3. Zewen Liu
4. Tingyang Zhou
5. Andrew J. Saykin

In Pharmacology

1. L. Zuo
2. Zewen Liu
3. Tingyang Zhou

In Physiology

1. K. Rahman
2. L. Zuo
3. Zewen Liu
4. Hannah J. Zhang
5. K. Kregel
6. Tingyang Zhou

Citations in the corpus

• Oxidative Stress: A Key Modulator in Neurodegenerative Diseases (2019, background): “ROS is found to have a deleterious effect on lipids by being involved in lipid peroxidation to malondialdehyde (MDA), protein carbonyls, and oxidation of guanine into 8-oxo-deoxyguanosine in DNA [24,25].”
• Candidate mechanisms for chemotherapy-induced cognitive changes (2007, background): “Furthermore, oxidative DNA damage has been associated with various neurodegenerative disorders, including Alzheimers disease and Parkinsons disease, that are characterized by significant cognitive symptom”
• An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. (2007, background): “These molecules, acting both systemically and at the tissue level, can produce products that include both reactive oxygen and reactive nitrogen species (153, 187, 214, 249, 284), and it is postulated that the accumulation of these reactive species contributes to the pathogenesis of age-related disea”
• Role of ROS and Nutritional Antioxidants in Human Diseases (2018, background): “STATUS IN AGING Free radical theory, which was first proposed by Harman in 1956, suggests that aging is process related with progressive and irreversible accumulation of oxidative damage in the cells (Harman, 1956; Mariani et al., 2005).”
• Studies on free radicals, antioxidants, and co-factors (2007, background): “Increased levels of oxidative damage to DNA and evidence for lipid peroxidation has also been demonstrated in ischemic stroke patients (Mariani et al 2005).”