Using the transcriptome to annotate the genome
By Saurabh Saha, A. Sparks, C. Rago, V. Akmaev, Clarence J. Wang, Bert Vogelstein, Kenneth W. Kinzler, Victor E. Velculescu. Nature Biotechnology, 2002
644 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/c30f6a2c7c03af450b008ee13af5fc04283868c4
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In Molecular Biology
- L. Diaz
- Victor E. Velculescu
- Bert Vogelstein
- Philipp Kapranov
- Kenneth W. Kinzler
- Olena Morozova
- Colin C. Collins
- F. McCormick
Citations in the corpus
- Chromosome aberrations in solid tumors (2003, background): “Serial analysis of gene expression (SAGE) provides unbiased, quantitative analyses of gene expression but at comparatively high cos”
- Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004, neutral): “It is a condition of access that users recognise and abide by the legal requirements associated with these rights.”
- Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. (2004, background): “…RNAs on chromosomes 21been detected in the human genome (Chen et al., 2002; and 22 (and by extension the entire human genome)Kapranov et al., 2002; Saha et al., 2002), it has been strongly argue that many of these RNAs have biologicalunclear whether these RNAs represent transcriptional functions…”
- Mutant PIK3CA promotes cell growth and invasion of human cancer cells. (2005, background): “, 1995) or SAGE technologies (Saha et al., 2002; Velculescu et al., 1995) should therefore be particularly informative.”
- Applications of next-generation sequencing technologies in functional genomics. (2008, methodology): “[52] has described an extension of the SAGE method based on the LongSAGE protocol [54], for generation of longer tags of 17 bp versus 14 bp in the original SAGE, and the 454 sequencing technology.”
- Physiology and molecular biology of stress tolerance in plants (2006, methodology): “This method relies upon the generation of unique short sequences, 9-17 base pairs (Velculescu et al., 1995; Saha et al., 2002) which contain sufficient information to identify a transcript (Fig.”