Nucleation of protein fibrillation by nanoparticles

By S. Linse, C. Cabaleiro-Lago, Wei-Feng Xue, Iseult Lynch, S. Lindman, E. Thulin, S. Radford, Kenneth A. Dawson. Proceedings of the National Academy of Sciences of the United States of America, 2007

836 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/c2fc04c74c4659b830982464492c48ae8100fa0d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. A. Nel
2. R. Owen
3. Kenneth A. Dawson
4. Iseult Lynch
5. Tian Xia
6. J. Lead
7. M. Liong
8. J. Zink

In Molecular Biology

1. Kenneth A. Dawson
2. Iseult Lynch
3. Elif S. Seven
4. Zhili Peng
5. Tian Xia
6. R. Owen
7. A. Nel
8. M. Liong

Citations in the corpus

• Crossing the blood‐brain barrier with nanoparticles (2018, background): “However, after the initial observation of Linse and coworkers about the fibril formations [44] there has been studies that showed that some types of NPs can have therapeutic effects rather than induction of the neurodegenerative diseases.”
• Molecular Toxicity Mechanism of Nanosilver (2014, neutral): “[115] Linse S, Cabaleiro-Lago C, Xue W-F, et al.”
• Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults (2008, background): “Ultrafine PM could play a role in the enhancement rate of protein fibrillation affecting Aβ42 and α-synuclein (Linse et al. 2007).”
• Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle (2013, neutral): “formation [39].”
• Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications (2013, background): “The influence of nanoparticles on protein fibrillation has also been shown [105].”
• Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties (2018, background): “In vitro experiments have demonstrated that QDs coated with a hydrophilic polymer accelerate the formation of fibrils of human β2 microglobulin, which are then arranged into multilayered structures on the particle surface; this results in a local increase in the protein concentration on the NP surfa”
• The ecotoxicology and chemistry of manufactured nanoparticles (2008, background): “, Linse et al. 2007) further suggest that interaction of NPs with proteins may also be important in sublethal responses. Linse et al. (2007) used in vitro experiments with buffers containing soluble proteins and exposure to hydrophobic NPs (CeO, MWCNTs, polymer-coated quantum dots) to show an increa”
• The Adverse Effects of Air Pollution on the Nervous System (2012, background): “a possible link between air pollution and neurodegenerative disorders [143, 144].”