Insulin resistance and cardiovascular disease.

By B. Egan, E. Greene, T. Goodfriend. American Journal of Hypertension, 2001

1,148 citations recorded by the source corpus.

Subfields: Biochemistry, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/c2a49e607a11f8ee734a34c2451ab834ce011afd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. Sushil Kumar Jain
2. Prasenjit Manna

In Epidemiology

1. Lorraine O'Driscoll
2. Sadhbh O’Neill
3. M. Ibrahim
4. Sushil Kumar Jain
5. Prasenjit Manna
6. K. Frayn
7. R. Eckel
8. E. Ferrannini

In Physiology

1. Marja-Riitta Taskinen
2. M. Ibrahim
3. Sushil Kumar Jain
4. K. Frayn
5. R. Eckel
6. J. Sowers
7. Barry J. Goldstein
8. Rosario Scalia

Citations in the corpus

• Subcutaneous and visceral adipose tissue: structural and functional differences (2010, background): “Only obese individuals characterized by increased VAT show the complications predictive of type 2 diabetes and cardiovascular disease (51).”
• Diabetic dyslipidaemia: from basic research to clinical practice* (2003, background): “In contrast, chronically increased flux of NEFA to the liver increases the cytosolic triglyceride storage pool and promotes VLDL overproduction, reducing post-translational degradation of apo B and overexpression of MTP, both associated with insulin resistance [42, 63].”
• Adipose tissue as a buffer for daily lipid flux (2002, background): “We are aware, of course, of many authors who have described links between obesity and insulin resistance, diabetes or cardiovascular disease in terms of increased NEFA flux and impaired fatty uptake by adipocytes [2, 94, 95, 96].”
• Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies (2015, background): “Obesity is associated with higher concentrations of the hormones in the renin–angiotensin system.(79) Increased concentrations of angiotensin II may promote oxidative stress in vasculature through several mechanisms, including activation of NOX, formation of O2 , and production of H2O2.”
• Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies (2015, background): “Fifty per cent of hypertensive people are insulin resistant (49).”
• α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population (2010, background): “Insulin resistance (IR) has been established as a precursor of type 2 diabetes (T2D) [1,2,3,4,5,6] and cardiovascular disease [7,8,9,10,11].”
• Metformin: An Update (2002, background): “Impaired vascular insulin action may result in impaired nitric oxide– dependent vascular relaxation, decreased sodium pump activity, and increased levels of [Ca(2) ]i in vascular smooth muscle in patients with type 2 diabetes (14, 63, 92).”
• The metabolic syndrome. (2008, methodology): “Alternatively, insulin-resistant individuals demonstrate impaired glucose metabolism or tolerance by an abnormal response to a glucose challenge, elevated fasting glucose levels and/or overt hyperglycemia, or reductions in insulin action after iv ad784 Endocrine Reviews, December 2008, 29(7):777–822”
• Insulin resistance and chronic cardiovascular inflammatory syndrome. (2003, neutral): “In 282 Endocrine Reviews, June 2003, 24(3):278–301 Fernández-Real and Ricart • Insulin Action, Inflammation, and Atherosclerosis”