Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons

By Jackie Schiller, Y. Schiller, G. Stuart, Bert J. Sakmann. 1997

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Citations in the corpus

Single‐shock LTD by local dendritic spikes in pyramidal neurons of mouse visual cortex (2004, background): “Besides these sodium spikes, which can also be initiated in the dendrite (Golding & Spruston, 1998), neocortical pyramidal neurons or CA1 neurons also have dendritic calcium spikes (Amitai et al. 1993; Schiller et al. 1997).”
Integrative properties of radial oblique dendrites in hippocampal CA1 pyramidal neurons. (2006, background): “…spikes and dendritic spiking mechanisms have been reported for CA1 and L5 pyramidal neurons (Ariav et al., 2003; Cai et al., 2004; Gasparini et al., 2004; Gasparini and Magee, 2006; Golding and Spruston, 1998; Larkum et al., 2001; Polsky et al., 2004; Schiller et al., 1997, 2000; Wei et al., 2001).”
The role of single neurons in information processing (2000, background): “The preferred direction of action potential propagation under physiological conditions and the degree of boosting of local inputs are being actively investigate”
Dopamine Receptor Signaling (2004, background): “N- and P/Qtype channel activation produces Ca2þ spikes mainly within more distal dendritic regions of somotosensory (64) but not prefrontal cortical neurons (65).”
Models of Neocortical Layer 5b Pyramidal Cells Capturing a Wide Range of Dendritic and Perisomatic Active Properties (2011, background): “The second spiking zone is located at the distal apical dendrites [7,21–22], where Ca spikes are generated in response to an intense dendritic [22] or somatic [23] stimulation in vitro.”
The principal features and mechanisms of dopamine modulation in the prefrontal cortex. (2004, background): “In contrast, large amplitude and duration Ca spikes are readily observed in the distal apical dendrites of adult somatosensory neurons (Schiller et al., 1997; Stuart et al., 1997; Larkum et al., 1999a; Zhu, 2000; Larkum and Zhu, 2002).”
Pyramidal neurons: dendritic structure and synaptic integration (2008, background): “The briefest spikes are called Na + spikes, even though there is some Ca 2+ influx associated with these events; larger, broader dendritic spikes are usually called Ca 2+ spike”