Challenges and solutions for the delivery of biotech drugs--a review of drug nanocrystal technology and lipid nanoparticles.

By R. Muller, C. Keck. Journal of Biotechnology, 2004

849 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/c1027d0722b48ea64c7f6ec7f517f8c6cc1324a8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. D. McClements

In Molecular Biology

1. D. McClements
2. I. Rubinstein
3. Jiajia Rao
4. O. Koo
5. M. Üner
6. J. Weiss
7. H. Onyuksel
8. P. Augustijns

In Pharmaceutical Science

1. I. Rubinstein
2. Jiajia Rao
3. O. Koo
4. M. Üner
5. J. Weiss
6. H. Onyuksel
7. D. McClements
8. P. Augustijns

Citations in the corpus

• Structural Design Principles for Delivery of Bioactive Components in Nutraceuticals and Functional Foods (2009, background): “By crystallizing the lipid phase it is often possible to control the physical location of a lipophilic component and to slow down molecular diffusion processes, thereby increasing the stability of chemically labile components (Yang et al., 2006; Zhang et al., 2004; Sivaramakrishnan et al., 2004; Vid”
• Applications of nanotechnology for immunology (2013, background): “An active drug is incorporated and delivered by the carrier, which is chosen on the basis of composition, size and charge 92, 106 .”
• Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products. (2008, background): “…1998; Müller et al., 1999a; Müller et al., 1999b; Müller et al., 2000a; Müller et al., 2000b; Müller et al., 2001; Merisko-Liversidge et al., 2003; Müller and Keck, 2004; Patravale et al., 2004; Rabinow, 2004; Rao et al., 2004; Gupta, 2006), their manufacturing techniques (Jahnke, 1998; Horn and…”
• Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives (2007, background): “All rights reserved International Journal of Nanomedicine 2007:2(3) 289–300 289 Melike Üner Gülgün Yener 1Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Beyazit 34119 Istanbul, Turkey Correspondence: Melike Üner Istanbul University, Faculty of Pharmacy, Department”
• Food-Grade Nanoemulsions: Formulation, Fabrication, Properties, Performance, Biological Fate, and Potential Toxicity (2011, background): “The oil droplets can then be crystallized after their formation by cooling the nanoemulsion sufficiently below the melting temperature of the lipid (Walstra, 2003; Muller and Keck, 2004; Wissing et al., 2004; McClements, 2005).”