The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
By Ying Wang, C. Wan, L. Deng, Ximeng Liu, Xuemei Cao, S. Gilbert, M. Bouxsein, M. Faugere, R. Guldberg, L. Gerstenfeld and 4 more. Journal of Clinical Investigation, 2007
728 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/c0770e4002d0f2a07bbd6fbead7fe4fb06dfebd1
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Citations in the corpus
- Guidelines for assessment of bone microstructure in rodents using micro–computed tomography (2010, background): “…to ischemic injury, (84,85) phenotypic characterization of tissue repair and remodeling, (85) therapeutic angiogenesis, (83) postnatal development and growth, (100,101) cerebral circulation, (102) vascular biomechanics and disease, (103) fracture healing, (35) and tissue engineering (104,105) (Fig.”
- Osteogenesis and angiogenesis: the potential for engineering bone. (2008, background): “…shown that inhibition of VEGF signalling leads to i) a dose-dependent increase in the femoro-tibial epiphyseal growth plate zone of hypertrophy (Wedge et al., 2002), ii) reduced angiogenesis in growth plates, iii) loss of metaphyseal blood vessels and, iv) a reduction in trabecular bone…”
- Hypoxia-Inducible Factors in Physiology and Medicine (2012, background): “…production of cartilage) (Schipani et al., 2001), adipogenesis (Yun et al., 2002), B lymphocyte development (Kojima et al., 2002), osteogenesis (Wang et al., 2007), hematopoiesis (Takubo et al., 2010), T lymphocyte differentiation (Dang et al., 2011), and innate immunity (Zinkernagel et al.,…”