The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis

By Peter Fransson, Guillaume Marrelec. NeuroImage, 2008

1,229 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/c06d52d23daaa1a3824fbdc0f2b20a66ad299420

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Citations in the corpus

Default and Executive Network Coupling Supports Creative Idea Production (2015, background): “For example, the precuneus—a core hub of the DMN (20)—has been implicated in both structural (21-24) and functional”
Functional-Anatomic Fractionation of the Brain's Default Network (2010, neutral): “The PCC, in particular, correlates with all regions that fall within the default network, even after taking the correlation between other default network regions into account (Fransson and Marrelec, 2008).”
Investigating the Functional Heterogeneity of the Default Mode Network Using Coordinate-Based Meta-Analytic Modeling (2009, result): “6), in agreement with other studies that this cortical region is a critical node in the DMN (Raichle et al., 2001; Greicius et al., 2003; Fransson and Marrelec, 2008).”
Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients. (2010, background): “This finding is coherent with studies showing a central role of precuneus in DMN architecture, from the functional (Fransson and Marrelec, 2008) to the structural point of view (Hagmann et al.”
The Brain’s Default Network and its Adaptive Role in Internal Mentation (2011, background): “Consistent with its widespread pattern of connectivity, the PCC appears to play a key integrative role, being significantly functionally correlated with all other default network regions even after taking their pairwise regional correlations into account (e.g., Fransson and Marrelec 2008).”
Network centrality in the human functional connectome. (2012, neutral): “patterns of results have been reported (Fransson and Marrelec 2008; Hagmann et al. 2008; Buckner et al. 2009; He et al. 2009; Fransson et al. 2011).”
Eigenvector Centrality Mapping for Analyzing Connectivity Patterns in fMRI Data of the Human Brain (2010, background): “Recent literature postulated that posterior midline cortex, comprising precuneus and posterior cingulate cortex constitutes the core hub within the default network of the human brain with strong connections to ventral medial prefrontal cortex/ anterior cingulate cortex, inferior lateral parietal cor”
Functional connectivity mapping of the human precuneus by resting state fMRI (2012, background): “…et al., 2003, 2005), and visuospatial processing (Kawashima et al., 1995; Wenderoth et al., 2005), as well as showing greater activity during resting as compared to responding to an external task (Fransson and Marrelec, 2008) (see also (Cavanna, 2007; Cavanna and Trimble, 2006) for review).”
Intrinsic architecture underlying the relations among the default, dorsal attention, and frontoparietal control networks of the human brain (2012, neutral): “Within-network connectivity was consistent with prior characterizations of the spatial extent of the default, dorsal attention, and frontoparietal control networks (e.g. Vincent et al., 2008) and with partial correlations within the default network (Fransson & Marrelec, 2008).”
Amyloid deposition is associated with impaired default network function in older persons without dementia (2009, positive): “…network show structural and functional connectivity that converges on the posterior cingulate extending into the precuneus (Buckner et al., 2008; Fransson and Marrelec, 2008; Greicius et al., 2009; Hagmann et al., 2008), which is strongly interconnected with the hippocampal formation (Greicius…”
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer’s Disease (2009, background): “The posterior midline, in particular the posterior cingulate, is a nexus of cortical connectivity and has among the highest levels of both degree and betweenness centrality (Achard et al., 2006; Buckner et al., 2008; Fransson and Marrelec, 2008; Hagmann et al., 2008; Greicius et al., 2009).”
Salience network integrity predicts default mode network function after traumatic brain injury (2012, background): “The precu/PCC region is the central node of the DMN (23) and forms part of what has been termed the structural core of the brain (37).”
The resting brain: unconstrained yet reliable. (2009, background): “The analysis of functional connectivity between sets of a priori ROIs represents one fruitful approach to the study of fcMRI (Achard et al. 2006; Dosenbach et al. 2007; Fair et al. 2007; Fransson and Marrelec 2008).”
Echoes of the Brain within the Posterior Cingulate Cortex (2012, methodology): “For example, a predominantly ventral region shows strong functional connectivity to the rest of the DMN, whereas two subregions within the dorsal PCC show high connectivity to frontoparietal networks involved in cognitive control.”