AGE‐RELATED CHANGES IN THE STRUCTURE AND FUNCTION OF SKELETAL MUSCLES

By J. Faulkner, L. Larkin, D. Claflin, S. Brooks. Clinical and Experimental Pharmacology and Physiology, 2007

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A Review of Non-Invasive Techniques to Detect and Predict Localised Muscle Fatigue (2011, background): “When muscle activation occurs to lift a load, the muscle shortens and contracts [6].”
The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size. (2013, background): “The efficacy of interventions designed to combat sarcopenia depends on their ability to affect those processes that play a role in the etiology of sarcopenia (Dirks and Leeuwenburgh, 2005; Faulkner et al., 2007).”
The age-related loss of skeletal muscle mass and function: Measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans (2018, background): “Loss of muscle fibres is associated with the age-related loss of motor units (MU) (Faulkner et al., 2007; Hepple and Rice, 2016; Piasecki et al., 2016b).”
Cell and Molecular Biology (2009, background): “In humans, a gradual loss of muscle fibers begins at approximately 50 years of age and continues such that by 80 years of age, approximately 50% of the fibers are lost from the limb muscles that have been studied (Faulkner et al., 2007).”
Motor control and aging: links to age-related brain structural, functional, and biochemical effects. (2010, neutral): “Such variability may arise from peripheral changes in the neuromuscular system (cf. Faulkner et al., 2007) or may arise from increased neural noise at the central nervous system level (cf. Welford, 1956).”