The use of a plus-maze to measure anxiety in the mouse

By R. Lister. Psychopharmacology, 2004

2,290 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/beac12f419c04eb607e8cb16db740dd7464600f2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. M. Meunier-Salaün
2. Ted Abel
3. R. B. Jones
4. E. Canali
5. Avishek Adhikari
6. J. Gordon
7. J. Blendy
8. F. Tirone

In Cognitive Neuroscience

1. M. Meunier-Salaün
2. Ted Abel
3. R. B. Jones
4. E. Canali
5. Avishek Adhikari
6. J. Gordon
7. J. Blendy
8. B. Forkman

In Social Psychology

1. M. Meunier-Salaün
2. Ted Abel
3. R. B. Jones
4. E. Canali
5. Avishek Adhikari
6. J. Gordon
7. J. Blendy
8. B. Forkman

Citations in the corpus

• Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety (2010, positive): “Percentage of time spent and path length in the center of the open field, as well as percentage of time spent and entries into the open arms of the EPM, were used as pharmacologically validated measures of anxiety-like behavior (Choleris et al., 2001; Lister, 1987).”
• Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on. (2005, background): “…to the behavioral changes, although early results showed that repeated testing did not modify baseline open arm exploration (Pellow et al., 1985; Lister, 1987; File et al., 1990), nowadays there is growing evidence that it increases open arm avoidance during Trial 2 (Lee and Rodgers, 1990;…”
• A critical review of fear tests used on cattle, pigs, sheep, poultry and horses. (2007, methodology): “The design is a modification of the apparatus commonly used as behavioral models of fear in rodents [92,93] adjusted to the size of young pigs (6 – 7 weeks, [69,70 This response was related to anxiety whereas the number of entries into closed arms unaffected by the diazepam treatment was related to…”
• Behavioral analysis of CREB αΔ mutation on a B6/129 F1 hybrid background (2002, methodology): “In order to understand if CREB mice have altered levels of anxiety, we tested their performance in the elevated plus maze (Lister, 1987).”
• The Timing of Differentiation of Adult Hippocampal Neurons Is Crucial for Spatial Memory (2008, positive): “All mice were tested in an open field and a plus maze [85,86] to assess locomotor abilities and anxiety levels.”
• Enhanced Learning and Memory and Altered GABAergic Synaptic Transmission in Mice Lacking the α5 Subunit of the GABAAReceptor (2002, methodology): “maze, an unconditioned model of anxiety (Lister, 1987).”
• Metabotropic glutamate receptors as novel targets for anxiety and stress disorders (2005, background): “The ELEVATED PLUS MAZE (EPM) is a widely used anxiety model that exploits the rodent's innate aversion to heights and open spaces, and anxiolytic benzodiazepine agents such as diazepam are highly effective anxiolytics as measured by an increasing exploration of the open ar”