Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

By C. Swanson, M. Bures, Michael P. Johnson, A. Linden, J. Monn, D. Schoepp. Nature reviews. Drug discovery, 2005

625 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/48f66fddc09ad5a101114a3d9894fd553d6c7892

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. E. Nestler
2. O. Berton
3. Craig Lindsley
4. Arthur Christopoulos
5. D. Schoepp
6. G. Collingridge
7. G. Koob
8. R. Duman

In Molecular Biology

1. Craig Lindsley
2. P. Conn
3. E. Nestler
4. Arthur Christopoulos
5. D. Schoepp
6. G. Collingridge
7. G. Koob
8. Colleen A. Mcclung

In Social Psychology

1. E. Nestler

Citations in the corpus

• New approaches to antidepressant drug discovery: beyond monoamines (2006, background): “One proposed strategy would be to target any of several metabotropic (or G-protein-coupled) glutamate receptors, which seem to differentially modulate the activity of the ionotropic receptors and might thereby mediate safer and more selective effect”
• Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders (2009, background): “Multiple studies have established robust efficacy of mGluR5 NAMs in several animal models of anxiolytic activit”
• Metabotropic glutamate receptors: From the workbench to the bedside (2010, background): “Treatment with LY354740 is highly effective in several animal models of anxiety and panic disorders with no reductions of activity on repeated dosing (reviewed by Swanson et al., 2005).”