Early motor activity drives spindle bursts in the developing somatosensory cortex

By Rustem Khazipov, Anton M. Sirota, X. Leinekugel, G. Holmes, Yehezkel Ben-Ari, György Buzsáki. Nature, 2004

607 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/be61eaad084c0345bb76b9c6d2b03078819d3c5a

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Citations in the corpus

GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations. (2007, background): “Khazipov et al., 2004 Hippocampus Rat P1–30 Slice, CA3 pyramidal cells Field potential Bicuculline action switches from depressing to increasing CA3 MUA at P12 (3.5 mM external K ϩ ) and at P23 (8.5 mM external K ϩ ).”
Theta rhythm of navigation: Link between path integration and landmark navigation, episodic and semantic memory (2005, background): “A spatial metric in sensory systems cannot arise without movement of the body (Thompson and Varela, 2001; Khazipov et al., 2004), which is an essential part of dead reckoning navigation.”
Twitching in Sensorimotor Development from Sleeping Rats to Robots (2013, background): “But beginning ten years ago with the discovery that twitches trigger so-called spindle bursts (brief oscillatory events) in the somatosensory cortex of newborn rats [33], it became clear that the sensory experience of the sleeping infant is not as impoverished as it once seemed.”
Delayed Development of Adult-Generated Granule Cells in Dentate Gyrus (2006, background): “Networks in the neonatal visual system (Katz and Shatz, 1996), motor system (Khazipov et al., 2004), olfactory bulb (Yu et al.”
Revealing neuronal function through microelectrode array recordings (2015, unknown): “We then review relevant applications of MEAs for the study of single neurons and networks using various techniques and preparations.”
Scaling Brain Size, Keeping Timing: Evolutionary Preservation of Brain Rhythms (2013, unknown): “Whereas brain oscillations undergo dramatic changes during development (Matousek and Petersen, 1973; Gou et al., 2011; Khazipov et al., 2004; 2008), power spectral patterns in the alpha-beta band during sleep are remarkably stable in adults and allow for up to 90% correct discrimination among…”
Klusters, NeuroScope, NDManager: a free software suite for neurophysiological data processing and visualization. (2006, background): “…well-integrated applications, including NeuroScope (http://neuroscope.sourceforge.net), an dvanced viewer for electrophysiological and behavioral data with limited editing capabilities, Klusters (http://klusters.sourceforge.net), a graphical luster cutting application for manual and…”
Regional slow waves and spindles in human sleep. (2011, unknown): “Asynchronous spindles were observed during development (Khazipov et al., 2004) or in nonphysiological conditions such as decortication, cortical depression, and acute stroke, where a nonfunctional cortex is not able to exert its normal synchronizing influence (Contreras et al., 1996, 1997;…”
Cation-chloride cotransporters and neuronal function. (2009, background): “Notably, Minlebaev et al. (2007) have shown that in the neonatal neocortex in vivo, blocking GABAergic transmission has little effect on the basic patterns of the generation of spontaneous events known as ''spindle bursts'' (Khazipov et al., 2004).”
Rhythms of the brain (2006, background): “As predicted from the lesion experiments in adult rats, cortical spindles remain localized or travel slowly in the newborn (Khazipov et al., 2004). For a large-scale and detailed computational modeling of sleep spindles and other thalamocortical rhythms, see Traub et al. (2002). demonstrate that wit”
Neural ensemble reactivation in rapid eye movement and slow-wave sleep coordinate with muscle activity to promote rapid motor skill learning (2020, background): “Furthermore, these early twitches are coordinated with spindle oscillations, the earliest patterned activity in the neocortex, implying a functional relationship between muscle twitches and brain activity during development [34].”
Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night (2016, background): “While some memories integrate content from single sensory modalities, requiring consolidation in only single cortical regions (such as motor cortex, Khazipov et al., 2004), many memories integrate multimodal sensory and cognitive information (Gibson and Maunsell, 1997), and require ’global’…”
Embodiment or envatment? Reflections on the bodily basis of consciousness (2010, background): “2003) and for determining the somatotopic functional organization of the somatosensory cortex (Khazipov et al. 2004).”