Effects of caffeine on human health

By S. Jordan, J. Eastwood, J. Rotstein, A. Hugenholtz, M. Feeley. Food Additives and Contaminants, 2003

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Coffee and Health: A Review of Recent Human Research (2006, background): “180 Although early case-control studies tended to show positive associations between caffeine intake and pancreatic, bladder and ovarian cancers, more recent and better-designed studies have not supported the hypothesis that coffee consumption contributes significantly to the risk of these cancer”
The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide (2010, background): “, caffeine, polyphenols, volatile aroma compounds and heterocyclic compounds, [25,50-52].”
A review of caffeine's effects on cognitive, physical and occupational performance. (2016, background): “…wide variety of benefits and risks have been attributed to affeine, but it is generally agreed that for healthy adults, daily conumption of up to 400 mg (∼5.5 mg kg−1 for a 75 kg individual) of affeine does not present a health risk (Doepker et al., 2016; Higdon nd Frei, 2006; Nawrot et al., 2003).”