Eris: an automated estimator of protein stability

By Shuangye Yin, Feng Ding, N. V. Dokholyan. Nature Methods, 2007

404 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bd913abea4a03eed6633bee2f8116a53cee926fb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. Jeffrey J. Gray
2. N. V. Dokholyan
3. Andrew Leaver-Fay
4. David Baker
5. Shuangye Yin
6. Aroop Sircar
7. Feng Ding
8. Elizabeth H. Kellogg

In Molecular Biology

1. Jeffrey J. Gray
2. David Baker
3. N. V. Dokholyan
4. Andrew Leaver-Fay
5. Aroop Sircar
6. Feng Ding
7. Shuangye Yin
8. Jiye Shi

Citations in the corpus

• Analysis and Modeling of the Variable Region of Camelid Single Domain Antibodies (2011, background): “The Eris server (33) predicts an average DDG of 1.”
• SPROUTS: a database for the evaluation of protein stability upon point mutation (2008, background): “Eris (20) and AUTO-MUTE (21) were not published at the time we began our project (February 2007).”
• Role of conformational sampling in computing mutation-induced changes in protein structure and stability (2010, background): “5,6 Although the above studies all report impressive correlations with experimental values, they use quite different energy functions and sampling strategies, hence it is not clear which features of the approaches are sufficient and necessary for good performance.”
• Rapid flexible docking using a stochastic rotamer library of ligands (2010, methodology): “27,32,33 In principle, we can model ligand conformational flexibility in the same way as amino acids using the ligand rotamers of STROLL.”