Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

By Jian-Feng Li, J. Norville, John D Aach, Matthew McCormack, Dandan Zhang, Jenifer Bush, George M. Church, Jen Sheen. Nature Biotechnology, 2013

1,388 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Information Systems

View Paper: https://www.semanticscholar.org/paper/bcc35a6299346a303732212644eaa9294821259b

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Citations in the corpus

• Response of plants to water stress (2014, background): “…restriction endonucleases, such as zinc finger nucleases (ZFN) or TAL-effector nucleases (TALEN; Shukla et al., 2009; Osakabe et al., 2010b; Zhang et al., 2010; Cermak et al., 2011), and more recently, the CRISPR/CAS system (Li et al., 2013; Nekrasov et al., 2013; Shan et al., 2013).”
• A CRISPR/Cas9 toolkit for multiplex genome editing in plants (2014, methodology): “The CRISPR/Cas system has been harnessed to achieve efficient genome editing in a variety of organisms, including bacteria, yeast, plants, and animals, as well as human cell lines [12-27].”
• Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice (2013, background): “During the time the manuscript for this publication was under review, three articles appeared providing evidence for successful expression of the Cas9/sgRNA system in Arabidopsis and tobacco (46, 47) and in rice and wheat (48).”
• The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation. (2014, background): “…editing in human cell lines, zebra fish and mouse (Cong et al., 2013; Hwang et al., 2013; Wang et al., 2013) and recently applied to gene modification in plants (Feng et al., 2013; Jiang et al., 2013; Li et al., 2013; Mao et al., 2013; Miao et al., 2013; Nekrasov et al., 2013; Shan et al., 2013).”
• CRISPR/Cas9 in Genome Editing and Beyond. (2016, background): “The use of the Cas9 platform has greatly increased the efficiency of generating transgenic organisms, from fungi (32) and plants (33, 34, 97, 98) to a variety of animals (5–7, 36, 99–102) (reviewed in 9, 10, 35).”
• Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins (2014, background): “…to modify genomes in various species including model organisms (Cho et al. 2013b; Dickinson et al. 2013; Friedland et al. 2013; Gratz et al. 2013; Li et al. 2013a,c; Wang et al. 2013; Sung et al. 2014) and plants (Li et al. 2013b; Nekrasov et al. 2013; Shan et al. 2013), rapidly catching up with…”
• Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. (2013, background): “Recently, several groups have demonstrated the use of the CRISPR/Cas9 system for genome engineering in various species (Chang et al., 2013; Cho et al., 2013; Cong et al., 2013; Friedland et al., 2013; Hou et al., 2013; Hwang et al., 2013; Jinek et al., 2013; Li et al., 2013; Mali et al., 2013; Nekra”
• Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis (2014, background): “It was shown that engineered CRISPR/Cas caused mutations in target genes or corrections in transgenes in transient expression assays in plant protoplasts and tobacco leaves (10).”
• Genome Editing of Plants (2017, methodology): “…1990; Lee et al., 1990; Miao and Lamb, 1995; Puchta et al., 1996; Terada et al., 2002, 2007; D’Halluin et al., 2008; Cai et al., 2009; de Pater, 2013; Li et al., 2013; Zhang et al., 2013; Qi et al., 2013a; Svitashev et al., 2015) as well as nonintegrating viruses (Vainstein et al., 2011; Baltes et…”
• Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA[OPEN] (2015, background): “As a result, reports describing successful gene editing or site-specific trait gene integration through HDR in plants are limited (Cai et al., 2009; Shukla et al., 2009; Townsend et al., 2009; Ainley et al., 2013; D’Halluin et al., 2013; Li et al., 2013; Shan et al., 2013; Zhang et al., 2013).”