The snail superfamily of zinc-finger transcription factors

By M. Nieto. Nature reviews. Molecular cell biology, 2002

1,761 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bc17fe31fd4299ba7b66298f5e746db4bf4e9873

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In Genetics

1. R. Weinberg
2. M. Nieto
3. Raghu Kalluri
4. J. P. Thiery
5. Jing Yang
6. J. Massagué
7. E. Hay
8. A. Cano

In Molecular Biology

1. R. Weinberg
2. M. Nieto
3. J. Massagué
4. J. P. Thiery
5. Raghu Kalluri
6. A. Cano
7. Jing Yang
8. E. Hay

Citations in the corpus

• Transcriptional regulation of cadherins during development and carcinogenesis. (2004, background): “In contrast, Slug null mice are viable, undergoing an apparently normal program of mesoderm and neural crest cell development (see Nieto, 2002).”
• Integrin signalling during tumour progression (2004, background): “pl?O43623">SLUG family of transcription factors suppress transcription of the E-cadherin gen”
• Snail blocks the cell cycle and confers resistance to cell death. (2004, background): “During development, they are involved in the ingression of the early mesodermal cells at gastrulation and in the delamination of the neural crest from the neural tube (Nieto 2002).”
• Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells (2005, background): “Recently, Snail, a transcription repressor, was shown to play a central role in epithelial–mesenchymal transition (Nieto, 2002).”
• The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. (2003, background): “Other potential modulators of E-cadherin transcription are SNAIL-related repressors, such as Slug, Smuc, and SIP1 that bind to E-boxes in the E-cadherin promoter (6, 32, 60).”
• Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex (2004, background): “Among them, the transcription factor Snail has been described as a strong repressor of E-cadherin in different murine and human carcinoma and melanoma cell lines and tumors (5, 9, 11, 13, 41, 48, 55) as well as during Drosophila and mouse embryo development (12, 25, 37, 38).”
• Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. (2004, background): “Expression of various snail family members has been tightly associated with cells undergoing both metastatic and developmental EMT (Nieto et al. 1992; Romano and Runyan 2000).”
• The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it (2005, background): “Thus, it is likely that EMT has evolved as the result of the evolution of anti–E-cadherin transcription factors, such as these repressors (Snail, Slug, Twist, LEF-1, and so on).”