The role of the right inferior frontal gyrus: inhibition and attentional control

By A. Hampshire, Samuel R. Chamberlain, M. Monti, John S. Duncan, Adrian M. Owen. NeuroImage, 2010

1,327 citations recorded by the source corpus.

There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a particular form of executive control referred to as response inhibition. However, tasks used to examine neural activity at the point of response inhibition have rarely controlled for the potentially confounding effects of attentional demand. In particular, it is unclear whether the RIFG is specifically involved in inhibitory control, or is involved more generally in the detection of salient or task relevant cues. The current fMRI study sought to clarify the role of the RIFG in executive control by holding the stimulus conditions of one of the most popular response inhibition tasks–the Stop Signal Task–constant, whilst varying the response that was required on reception of the stop signal cue. Our results reveal that the RIFG is recruited when important cues are detected, regardless of whether that detection is followed by the inhibition of a motor response, the generation of a motor response, or no external response at all.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/baaac1060a773bc8f49591e9eae2223bff6f1094

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In Cognitive Neuroscience

Citations in the corpus

Oscillatory Cortical Network Involved in Auditory Verbal Hallucinations in Schizophrenia (2012, background): “For the observed decrease in alpha-band power in the right inferior frontal gyrus several explanations are possible, including processing of linguistic emotional information, detection of salient events and dysfunctional inhibition processes [41–43].”
A computational model of inhibitory control in frontal cortex and basal ganglia. (2011, background): “Parent, A., & Hazrati, L. N. (1995). Functional anatomy of the basal”
Are the neural correlates of stopping and not going identical? Quantitative meta-analysis of two response inhibition tasks (2011, background): “Other recent findings suggest that the pre-SMA is specifically associated with response inhibition, while RIFG activations are involved in attentional capture (Sharp et al., 2010) and attentional control (Hampshire et al., 2010).”
Neural network of cognitive emotion regulation — An ALE meta-analysis and MACM analysis (2013, background): “Additionally, there is evidence that the VLPFC is a detector of salience rather signals when to inhibit and what to feel, than reflects the inhibitory process itself (Hampshire et al., 2010).”
“Roles for the pre-supplementary motor area and the right inferior frontal gyrus in stopping action: electrophysiological responses and functional and structural connectivity” (2011, background): “…both be important for inhibitory control, or one could be important in monitoring for the stop signal and/or detecting conflict and another for implementing inhibitory control (Duann et al., 2009; Hampshire et al., 2010; Mostofsky and Simmonds, 2008; Sharp et al., 2010; Verbruggen et al., 2010).”