Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial.

By Y. Freund-Levi, M. Eriksdotter‐Jönhagen, T. Cederholm, H. Basun, G. Faxén-Irving, A. Garlind, I. Vedin, B. Vessby, L. Wahlund, J. Palmblad. Archives of Neurology, 2006

753 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/ba9810f849afb13aaa59be8fa814f2022c9c8a68

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Citations in the corpus

Omega-3 fatty acids EPA and DHA: health benefits throughout life. (2012, background): “Memory loss is an early indicator of the disease, which is progressive, and leads to the inability of the patient to care for him- or herself and eventually to death (47).”
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013, background): “To date, the clinical effectiveness of DHA treatment is still controversial (Freund-Levi et al., 2006; Quinn et al., 2010).”
Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA (2015, result): “These results are consistent with a study showing positive effects in a sub-group of patients with very mild cognitive impairment (MMSE> 27) who were given a high DHA supplement (1.7 g DHA and 0.6 g EPA) for 6 months (Freund-Levi et al., 2006).”
Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease (2010, neutral): “Although the analysis in this study of the subpopulation of participants with baseline MMSE scores of greater than 20 failed to provide support for this hypothesis, other studies have reported post hoc analyses showing positive omega-3 fatty acid treatment effects in less impaired individuals, with ”