Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness.

By T. Kondo, Masashi Asai, Kayoko Tsukita, Y. Kutoku, Y. Ohsawa, Y. Sunada, K. Imamura, N. Egawa, Naoki Yahata, K. Okita and 33 more. Cell Stem Cell, 2013

728 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Pharmacology, Physiology

View Paper: https://www.semanticscholar.org/paper/7cb7b12a716693dffd6def57a6909317dfae1c08

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In Physiology

1. Thomas Wisniewski
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Citations in the corpus

• Alzheimer’s disease: experimental models and reality (2017, background): “Multiple groups have characterized iPSC lines from donor cells from FAD and sAD patients, which show increased production of Aβ, particularly Aβ42, and tau hyperphosphorylation in comparison to iPSCs derived from age-matched non-demented controls [66, 82, 101, 175].”