Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

By I. Tamai, J. Nezu, H. Uchino, Y. Sai, Asuka Oku, M. Shimane, A. Tsuji. Biochemical and Biophysical Research Communications - BBRC, 2000

648 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties (2004, background): “OATP1B1 was cloned from human liver [3, 29, 30, 31] and encodes a 691-amino-acid glycoprotein.”
OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies (2012, background): “OATP2B1 is also widely expressed throughout the body (Tamai et al., 2000; Kullak-Ublick et al., 2001).”
Impact of OATP transporters on pharmacokinetics (2009, background): “OATP3A1 transports estrone3-sulfate, prostaglandin E2, thyroxine, vasopressin and benzylpenicillin (Tamai et al., 2000; Huber et al., 2007).”
Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake (2011, methodology): “…sulfate, es- tradiol-17␤-D-glucuronide, and estrone-3-sulfate are substrates of OATP1B1 (Abe et al., 1999; König et al., 2000b; Tamai et al., 2000; Cui et al., 2001; Nakai et al., 2001; Tamai et al., 2001; Sasaki et al., 2002; Hirano et al., 2004; Kopplow et al., 2005;…”
Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation (2010, methodology): “Mouse Octn3 is the most selective transporter for carnitine, whereas Octn1 is the least (Tamai et al., 2000b).”