Impact of OATP transporters on pharmacokinetics

By A. Kalliokoski, M. Niemi. British Journal of Pharmacology, 2009

949 citations recorded by the source corpus.

Subfields: Oncology, Pediatrics, Perinatology and Child Health, Pharmacology

View Paper: https://www.semanticscholar.org/paper/269bbd41afe1561326744efba994b06aae91ad0e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Oncology

1. M. Roth
2. A. Obaidat
3. Christoph Borner
4. B. Hagenbuch
5. J. L. Boyer

Citations in the corpus

• Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression (2014, background): “6G), an organic ion transporter implicated in the transport of large molecules including eicosanoids, leukotrienes, steroids, and certain drugs (52).”
• OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies (2012, background): “Functional OATP polymorphisms are reviewed in detail by Kalliokoski and Niemi (2009) and Konig (2011).”
• Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, positive): “…anionic drugs such as statins, antibiotics, sartans, angiotensin-converting enzyme inhibitors and anticancer drugs (Hagenbuch and Gui 2008; Kalliokoski and Niemi 2009; Kusuhara and Sugiyama 2009; Fahrmayr et al. 2010; Giacomini et al. 2010; Konig 2011; Roth et al. 2012), as well as a wide…”