Regulation of tight junction permeability by intestinal bacteria and dietary components.

By Dulantha Ulluwishewa, R. Anderson, W. McNabb, P. Moughan, J. Wells, N. Roy. Journal of NutriLife, 2011

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The intestinal barrier: a fundamental role in health and disease (2017, background): “A broad range of individual food substances have been tested in Caco-2 monolayers with divergent effects on TEER readings and epithelial flux parameters [55].”
The Gut Microbiota and Alzheimer’s Disease (2017, positive): “Aging is associated with an overstimulation of both innate and adaptive immune systems, resulting in a low-grade, chronic state of inﬂammation deﬁned as inﬂammaging (for review, see [86, 87]), which may increase gut permeability (“leaky gut”) and bacterial translocation (for review, see [88, 89]).”
Intestinal permeability – a new target for disease prevention and therapy (2014, background): “A central regulator of this epithelial barrier is the intestinal microbiota [21].”
Impacts of Gut Bacteria on Human Health and Diseases (2015, background): “On the other hand, commensal bacteria and probiotics can promote barrier integrity, and prevent antigens and pathogens from entering the mucosal tissues [12].”