How widespread is adult neurogenesis in mammals?

By E. Gould. 2007

689 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Developmental Neuroscience

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In Cognitive Neuroscience

In Developmental Neuroscience

Citations in the corpus

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults (2018, neutral): “Labeled neuronal cells in the GCL in patients that received a low dose of BrdU 13 , could possibly be explained by processes not associated with cell division 27,28 (Extended Data Fig.”
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Neurogenesis in other adult CNS regions is generally believed to be very limited under normal physiological conditions but could be induced after injury (Gould, 2007).”
Emergence of multimodal action representations from neural network self-organization (2017, methodology): “…the process of neural growth of the GWR algorithm does not resemble biologically plausible mechanisms of neurogenesis (e.g., Eriksson et al., 1998; Gould, 2007; Ming & Song, 2011), it is an efficient learning model exhibiting a computationally convenient trade-off between adaptation to dynamic…”
BRAIN REGENERATION IN PHYSIOLOGY AND PATHOLOGY: THE IMMUNE SIGNATURE DRIVING THERAPEUTIC PLASTICITY OF NEURAL STEM CELLS (2011, background): “These assumptions have been recently challenged by data showing that neurogenesis also occurs in several other regions of the CNS, such as neocortex, cerebellum, striatum, amygdala, and substantia nigra (51, 85, 94, 134, 159, 180) and more recently also in the hypothalamus (75, 85, 109, 110, 170) an”
Development of the Child's Brain and Behavior (2009, background): “…that neurogenesis continues in the hippocampus and olfactory bulb, but although neurogenesis has been reported in the neocortex, striatum, amygdala, and substantia nigra, the latter findings have been difficult to replicate consistently in the undamaged brain (for a review, see Gould, 2007).”
NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration. (2010, background): “However, EGFP+ neuronswere visible within several days after 4HT administration (at P30); if they developed from NG2+ cells, these progenitors would have had to transform into neurons with unprecedented speed because neurons derived from NSCs in the hippocampus and lateral ventricle require 1.5–2 we”
Preventing Mental, Emotional, and Behavioral Disorders Among Young People: Progress and Possibilities (2009, background): “The number of new neurons generated is small, however, and whether and to what extent these neurons are able to integrate into synaptic circuits and exert a significant functional influence in the brain are at present unclear (Ghashghaei, Lai, and Anton, 2007; Gould, 2007; Lledo, Alonso, and Grubb, ”
Mechanisms and functional implications of adult neurogenesis. (2008, neutral): “, Gould, E., and Shors, T.J. (2006). Is there a link between adult neu-”
Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal Behavior (2010, neutral): “A deeper understanding of the functional role of adult neurogenesis could come from studying the physiological conditions in which this process is regulated; such a modulation has been IntroductIon Adult neurogenesis is conserved in a variety of animals, ranging from insects to humans (reviewed in L”
Adult neurogenesis and the olfactory system. (2009, background): “The occurrence of adult neurogenesis in other brain regions remains controversial (Gould, 2007).”
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain (2008, neutral): “However, these methods have only limited specificity and/or efficienc”
Age Differences in Hippocampal Subfield Volumes from Childhood to Late Adulthood (2015, background): “In younger age, the combination of selective neuronal pruning (see Luo and O’Leary, 2005; Holtmaat and Sboboda, 2009 for reviews) and neuropil changes, with possible local contribution of neurogenesis (Gould, 2007) may affect subfield volumes.”