Plant NBS-LRR proteins: adaptable guards

By L. McHale, Xiaoping Tan, Patrice Koehl, Richard W. Michelmore. Genome Biology, 2006

948 citations recorded by the source corpus.

The majority of disease resistance genes in plants encode nucleotide-binding site leucine-rich repeat (NBS-LRR) proteins. This large family is encoded by hundreds of diverse genes per genome and can be subdivided into the functionally distinct TIR-domain-containing (TNL) and CC-domain-containing (CNL) subfamilies. Their precise role in recognition is unknown; however, they are thought to monitor the status of plant proteins that are targeted by pathogen effectors.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/b5f495f164c9f09d65a3c1c18da849f75b003883

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In Plant Science

1. Henning Redestig
2. Christophe Dessimoz
3. Cyril Zipfel
4. J. Lucas
5. Natasha M. Glover
6. J. Lamichhane

Citations in the corpus

• Advances in plant disease and pest management (2010, background): “TheArabidopsis genome has around 150 NBS-LRR encoding genes and rice c. 400 (McHale et al. 2006).”
• Pattern-recognition receptors in plant innate immunity. (2008, background): “It is also unknown whether some of the 150 cytoplasmic NBSLRR proteins present in Arabidopsis [55], for example, could also act as intracellular PRRs, as recently demonstrated in mammals [56].”
• The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements (2014, background): “We chose not to be too stringent in the cut-off for evolutionary distance and/or percent identity because although most homeolog pairs have a high degree of conservation, this might not necessarily be true for certain genes that evolve quickly such as disease resistance genes (36), transcription fac”
• The genome of Theobroma cacao (2011, neutral): “Cacao chromosome Arabidopsis chromosome C1(1321) A1(63)-A2(85)-A3(69)-A4(116)-A5(64) C2(935) A1(89)-A2(30)-A4(61)-A5(10) C3(1018) A1(70)-A3(17)-A4(63)-A5(130) C4(837) A1(21)-A2(9)-A3(94)-A4(36)-A5(44) C5(820) A1(24)-A2(51)-A3(78)-A5(37) C6(616) A1(59)-A2(15)-A4(66)-A5(26) C7(287) A1(5)-A5(32) C8(605”